CVE-2026-31964
HTSlib CRAM decoder has a NULL Pointer Dereference
Description
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `CONST`, `XPACK` and `XRLE` encodings did not properly implement the interface needed to do this. Trying to decode records with omitted sequence or quality data using these encodings would result in an attempt to write to a NULL pointer. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
INFO
Published Date :
March 18, 2026, 7:16 p.m.
Last Modified :
March 18, 2026, 7:16 p.m.
Remotely Exploit :
Yes !
Source :
[email protected]
Affected Products
The following products are affected by CVE-2026-31964
vulnerability.
Even if cvefeed.io is aware of the exact versions of the
products
that
are
affected, the information is not represented in the table below.
No affected product recoded yet
CVSS Scores
| Score | Version | Severity | Vector | Exploitability Score | Impact Score | Source |
|---|---|---|---|---|---|---|
| CVSS 4.0 | MEDIUM | [email protected] |
Solution
- Update HTSlib to version 1.23.1 or later.
- Ensure CRAM decoding handles omitted data correctly.
References to Advisories, Solutions, and Tools
Here, you will find a curated list of external links that provide in-depth
information, practical solutions, and valuable tools related to
CVE-2026-31964.
| URL | Resource |
|---|---|
| https://github.com/samtools/htslib/commit/e64e68da567d2309509d059ace016d5d7fc7514f | |
| https://github.com/samtools/htslib/security/advisories/GHSA-5w97-85gf-86rm |
CWE - Common Weakness Enumeration
While CVE identifies
specific instances of vulnerabilities, CWE categorizes the common flaws or
weaknesses that can lead to vulnerabilities. CVE-2026-31964 is
associated with the following CWEs:
Common Attack Pattern Enumeration and Classification (CAPEC)
Common Attack Pattern Enumeration and Classification
(CAPEC)
stores attack patterns, which are descriptions of the common attributes and
approaches employed by adversaries to exploit the CVE-2026-31964
weaknesses.
We scan GitHub repositories to detect new proof-of-concept exploits. Following list is a collection of public exploits and proof-of-concepts, which have been published on GitHub (sorted by the most recently updated).
Results are limited to the first 15 repositories due to potential performance issues.
The following list is the news that have been mention
CVE-2026-31964 vulnerability anywhere in the article.
The following table lists the changes that have been made to the
CVE-2026-31964 vulnerability over time.
Vulnerability history details can be useful for understanding the evolution of a vulnerability, and for identifying the most recent changes that may impact the vulnerability's severity, exploitability, or other characteristics.
-
New CVE Received by [email protected]
Mar. 18, 2026
Action Type Old Value New Value Added Description HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `CONST`, `XPACK` and `XRLE` encodings did not properly implement the interface needed to do this. Trying to decode records with omitted sequence or quality data using these encodings would result in an attempt to write to a NULL pointer. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue. Added CVSS V4.0 AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:L/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X Added CWE CWE-476 Added Reference https://github.com/samtools/htslib/commit/e64e68da567d2309509d059ace016d5d7fc7514f Added Reference https://github.com/samtools/htslib/security/advisories/GHSA-5w97-85gf-86rm